Spurs were second best all over the pitch against their arch-rivals on Saturday, leaving Pochettino to demand what would be a morale-boosting victory at the Westfalenstadion.
Speaking to the club's official website, Pochettino insisted that a win in Germany is his only aim, despite having already qualified for the knockout stages.
'Now we have to keep going and get ready for Borussia Dortmund. Okay, we're already in the next stage of the competition but we want to win and try to change the feeling we have from the weekend,' he explained.
'It's always important to compete and to be focused on the next game and when you lose, it's important to play as soon as possible to change that feeling.'
Meanwhile, the Argentine also said that he is more than happy with the increased levels of expectation that now follow the club, as it means that his side are improving and developping.
'The expectation now is that we win the Champions League and Premier League and I am happy with the pressure and the criticism,' Pochettino explained.
'It means people expect more of us. We know very well we have improved in every single aspect.'
Finally, Spurs' Danish midfielder Chritian Eriksen echoed his manager's sentiments that the Dortmund game is a great opportunity for Spurs to get back to winning ways.
'It's probably good that we have a game so quickly after the derby and you can have a bit of revenge — you can show the world that you are better than what you saw on Saturday,' he admitted.